Tabriz University of Medical Sciences Journal of Research in Clinical Medicine 2717-0616 9 1 2021 01 01 Delayed Diagnosis of Congenital Hypothyroidism in a 6-month-old Male Infant in Tamale, Ghana. 22 22 10.34172/jrcm.2021.022 EN Alhassan Abdul-Mumin https://orcid.org/0000-0003-3792-5384 Kingsley A Bimpong https://orcid.org/0000-0002-4299-8919 Emmanuel Ameyaw https://orcid.org/0000-0001-5548-9905 Journal Article 10.34172/jrcm.2021.022 2021 03 03 2021 04 11 Congenital hypothyroidism is a common inborn endocrine disorder. Asymptomatic presentation in majority of cases mean that its diagnosis may be missed especially in settings where newborn screening is absent. We present a case of delayed diagnosis of congenital hypothyroidism and emphasize on need for high level of suspicion to aid prompt diagnosis and treatment. Our case is a 3 year, 4 months old male, who was first seen at 5 months of age on account of poor growth. He passed meconium after day four of life, developed jaundice in first week of life, and slept a lot in neonatal period. He had coarse faces, protruding tongue, widened anterior fontanelle and herniation of umbilicus. He was started on oral levothyroxine 50 microgram daily. In resources limited settings where universal newborn screening is absent, healthcare workers should have a high level of suspicion in picking up the early signs of the condition.