Tabriz University of Medical Sciences Journal of Research in Clinical Medicine 2717-0616 4 3 2016 08 10 Factors influencing dependence on mobile phone 158 162 10.15171/jarcm.2016.026 EN Mohammad-Hossein Biglu https://orcid.org/0000-0003-3353-7691 Mostafa Ghavami Journal Article 10.15171/jarcm.2016.026 2016 06 08 2016 07 25 Introduction: The purpose of current study was to investigate the relationship between the problematic use of mobile phone and Big Five personality traits among students of Tabriz University of Medical Sciences in Tabriz, Iran. Methods: A total number of 120 students (80 females and 40 males) were selected by applying proportional randomized classification sampling method from Tabriz University of Medical Sciences. The Mobile Phone Problematic Use Scale (MPPUS) and demographic questionnaire were used to gather data. Data were analyzed using SPSS software. Results: Analysis of gathered data showed that gender, neuroticism, extraversion, and openness to experience had positive correlation with the problematic use of mobile phone, whereas conscientiousness and agreeableness were not correlated with the problematic use of mobile phone. Conclusion: The evaluation of Big Five personality traits would be a reliable factor for predicting the problematic use of mobile phone among students.